All 11 ventilator modes — mechanisms, indications, key settings, and NBRC pearls.
Assist-Control / Volume Control
Synchronized Intermittent Mandatory Ventilation
Pressure Control
Pressure-Regulated Volume Control
Airway Pressure Release Ventilation
High-Frequency Oscillatory Ventilation
High-Frequency Jet Ventilation
CPAP
Bilevel Positive Airway Pressure
High-Flow Nasal Cannula
Pressure Support Ventilation
Delivers a set tidal volume with each breath (patient-triggered or mandatory). Every breath — whether triggered by the patient or by the machine — delivers the full set Vt. Guarantees minimum minute ventilation.
⚠ Watch Out
Breath stacking in tachypneic patients → auto-PEEP. Monitor with expiratory hold.
Delivers mandatory breaths at set rate synchronized to patient effort. Between mandatory breaths, patient breathes spontaneously (with or without pressure support). Mandatory breaths are volume-controlled.
⚠ Watch Out
Without adequate PS on spontaneous breaths, patients do extra work breathing through the ET tube resistance.
Sets an inspiratory pressure limit; delivers breaths to that pressure, with tidal volume varying based on compliance and resistance. Provides a decelerating flow waveform which improves gas distribution.
⚠ Watch Out
Compliance changes (pneumothorax, mucus plug, patient bucking) cause sudden Vt changes — alarm appropriately.
Dual-control mode: targets a set Vt while using the lowest possible inspiratory pressure. The ventilator measures compliance each breath and adjusts pressure up or down to hit the target Vt with a 5 cmH2O safety margin from Pmax.
⚠ Watch Out
Strong spontaneous efforts can cause the ventilator to reduce support, leading to breath stacking if the patient then triggers another breath.
Maintains a high continuous positive airway pressure (P-high) for a long time (T-high, typically 4–6 sec), then briefly releases to a low pressure (P-low ≈ 0) for a short time (T-low, typically 0.4–0.8 sec) to allow CO2 to escape. Patient breathes spontaneously throughout at P-high.
⚠ Watch Out
Do NOT use in COPD or asthma — incomplete exhalation during T-low causes air trapping.
Delivers very small tidal volumes (1–3 mL/kg) at very high frequencies (3–15 Hz) via a piston or diaphragm. Gas moves by convection, diffusion, and asymmetric velocity profiles. Mean airway pressure (MAP) controls oxygenation; amplitude (ΔP) controls CO2 removal.
⚠ Watch Out
Increasing frequency actually REDUCES CO2 clearance on HFOV — counterintuitive! Lower Hz = better CO2 removal.
Delivers high-velocity jets of gas through a small-bore injector cannula at 150–400 breaths/min. Extremely small tidal volumes. Primary use is minimizing airway pressure in pulmonary interstitial emphysema (PIE).
⚠ Watch Out
Air trapping risk — ensure adequate exhalation time despite high frequency.
Applies a constant positive pressure throughout the respiratory cycle. No additional ventilatory support — patient does ALL the work. Pressure splints the upper airway open and recruits alveoli.
⚠ Watch Out
If patient hypoventilates or has apnea on CPAP — there is no backup. Switch to BiPAP with backup rate or mechanical ventilation.
Applies two levels of pressure: IPAP (higher, during inspiration) and EPAP (lower, during expiration). The difference (IPAP − EPAP) provides pressure support, augmenting tidal volume. EPAP provides PEEP (oxygenation). Can have a backup rate.
⚠ Watch Out
Mask leak prevents effective pressure delivery. Refit mask before increasing pressures. If patient worsens despite optimization, intubate.
Delivers heated, humidified oxygen at flows of 20–60 L/min through a specialized nasal cannula. Mechanisms: meets/exceeds inspiratory flow demand (prevents FiO2 dilution), generates ~1–2 cmH2O PEEP per 10 L/min, flushes dead space (CO2), improves mucociliary clearance.
⚠ Watch Out
HFNC can mask worsening respiratory failure — reassess frequently. If FiO2 requirement is increasing, escalate early.
Applies a set positive pressure during patient-triggered inspiratory effort to augment Vt. The patient triggers EVERY breath — there is no mandatory rate. Flow cycles OFF when flow decreases to 25% of peak (or patient begins to exhale). Used during weaning and as support above PEEP.
⚠ Watch Out
In lung-protective ventilation, ensure PS+PEEP does not exceed lung-protective limits — patient-generated effort adds to circuit pressures.
For animated waveforms and the full clinical reference with Dräger/PB980 labels:
Vent Modes Reference Tool →