Understand pulmonary artery catheters, cardiac output, vascular resistance, and hemodynamic profiles.
90 min estimated
The pulmonary artery (PA) catheter (Swan-Ganz) is a balloon-tipped catheter floated from a central vein through the right heart and into the PA. It measures intracardiac and PA pressures and cardiac output.
Normal pressures: - CVP (RA): 2–6 mmHg - RV: 25/5 mmHg - PA systolic/diastolic: 25/8 mmHg; mean PA: 8–20 mmHg - PCWP (wedge): 6–12 mmHg
The wedge pressure (PCWP) reflects left atrial pressure and left ventricular preload. PCWP >18 mmHg suggests cardiogenic pulmonary edema; PCWP ≤18 mmHg in ARDS indicates non-cardiogenic cause.
Clinical Tip
Never leave the PA catheter balloon inflated — it occludes blood flow to a lung segment. Inflate briefly to measure wedge, then deflate immediately.
Cardiac output (CO) = HR × Stroke Volume. Normal CO: 4–8 L/min. Cardiac index (CI) normalizes for body size: CI = CO / BSA; normal 2.4–4.0 L/min/m².
Derived hemodynamic parameters: - SVR (systemic vascular resistance): normal 800–1200 dyn·s·cm⁻⁵ SVR = (MAP – CVP) / CO × 80 - PVR (pulmonary vascular resistance): normal <250 dyn·s·cm⁻⁵ PVR = (mPAP – PCWP) / CO × 80 - SvO2 (mixed venous O2 saturation): normal 60–75%; low SvO2 = inadequate delivery - DO2 (oxygen delivery): CaO2 × CO × 10; normal 950–1150 mL/min - VO2 (oxygen consumption): normal 200–250 mL/min
Clinical Tip
SvO2 is the best real-time indicator of global oxygen delivery-consumption balance. Trending SvO2 is more valuable than a single measurement.
Different shock states produce characteristic hemodynamic profiles:
Cardiogenic shock: ↓CO, ↑PCWP, ↑SVR, ↓SvO2 (heart can't pump, backs up fluid, vasoconstricts)
Distributive/septic shock: ↑CO (early), ↓SVR, ↓PCWP, ↓SvO2 or ↑SvO2 (vasodilation, high flow but poor extraction)
Hypovolemic shock: ↓CO, ↓PCWP, ↑SVR, ↓SvO2 (low volume, vasoconstricts to compensate)
Obstructive shock (PE/tension PTX): ↓CO, ↑PCWP (right side), ↑PVR, ↓SvO2
Mnemonic: ARDS: ↑ PA pressures, normal or low PCWP (non-cardiogenic); elevated PVR.
Clinical Tip
In suspected cardiac tamponade, all pressures equalize: CVP = RV diastolic = PCWP — the classic 'equalization of pressures' sign.
Identify the Shock Type
ICU patient: CO 2.1 L/min, PCWP 22 mmHg, SVR 1600, SvO2 48%, MAP 58 mmHg.
What type of shock is this and what is the recommended treatment?
Cardiogenic shock. Treatment: inotropes (dobutamine), diuresis if congested, possible IABP or mechanical support.
Classic cardiogenic profile: low CO (pump failure), high PCWP (fluid backs up into pulmonary vasculature), high SVR (compensatory vasoconstriction), low SvO2 (inadequate delivery). Dobutamine improves contractility; diuresis reduces preload if PCWP >18. Avoid aggressive fluid resuscitation.
Mechanical Ventilation
Master ventilator modes, initial settings, troubleshooting, weaning, and complications.
Cardiopulmonary Diagnostics
CXR interpretation, ECG basics, cardiac markers, and diagnostic procedures.
Adult Critical Care
Master ARDS, sepsis, shock management, and multisystem critical illness for the NBRC exam.