mechanics
Cst = VT ÷ (Pplat − PEEP)
Normal: 60–100 mL/cmH₂O
Normal: 400–600 mL
Normal: < 30 cmH₂O
Normal: 5–15 cmH₂O typically
Static compliance reflects the elastic recoil properties of the lung and chest wall combined. Measured during no-flow conditions (end-inspiratory pause), it reflects the true distensibility of the respiratory system without the confounding effect of airway resistance. Low static compliance means the lungs are stiff and require more pressure for the same volume.
Measure during volume-controlled ventilation by applying a 0.5–1 second inspiratory pause to obtain plateau pressure. Used to monitor lung condition in mechanically ventilated patients, diagnose ARDS, adjust PEEP, and guide lung-protective ventilation.
Normal mechanically ventilated patient
→ 29.4 mL/cmH₂O
Normal-low range — acceptable compliance
ARDS patient
→ 23.75 mL/cmH₂O
Low compliance — consistent with ARDS; consider adjusting PEEP and TV
Healthy patient post-surgery
→ 42.3 mL/cmH₂O
Good compliance — lungs are compliant
Falling static compliance indicates worsening pulmonary disease (ARDS progression, edema, pneumonia). Rising compliance may indicate improvement or recruitment. Compliance < 30 mL/cmH₂O suggests severe restrictive physiology. Used to calculate driving pressure (Pplat − PEEP), which independently predicts ARDS mortality.